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How Scientists and Engineers Got It Right, and VC’s Got It Wrong

Scientists and engineers as founders and startup CEOs is one of the least celebrated contributions of Silicon Valley. It might be its most important. ———- ESL, the first company I worked for in Silicon...

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Eureka! A New Era for Scientists and Engineers

Silicon Valley was born in an era of applied experimentation driven by scientists and engineers. It wasn’t pure research, but rather a culture of taking sufficient risks to get products to market...

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Scientists Unleashed

Some men see things as they are and ask why. Others dream things that never were and ask why not. George Bernard Shaw We’re in the middle of our National Science Foundation Innovation Corps class –...

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The Government Starts an Incubator: The National Science Foundation...

Over the last two months the U.S. government has been running one of the most audacious experiments in entrepreneurship since World War II. They launched an incubator for the top scientists and...

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The National Science Foundation Innovation Corps – Class 2: The Business...

The Lean LaunchPad class for the National Science Foundation Innovation Corps is a new model of teaching startup entrepreneurship. This post is part two. Part one is here. Syllabus here. The 21 NSF...

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The National Science Foundation Innovation Corps – What America Does Best

We ran the first National Science Foundation Innovation Corps class October to December 2011. 63 scientists and engineers in 21 teams made ~2,000 customer calls in 10 weeks, turning laboratory ideas...

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Making a Dent in the Universe – Results from the NSF I-Corps

Our goal teaching for the National Science Foundation was to make a dent in the universe. Could we actually teach tenured faculty how to turn an idea into a company?  And if we did, could it change...

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Reinventing Life Science Startups – Evidence-based Entrepreneurship

What if we could increase productivity and stave the capital flight by helping Life Sciences startups build their companies more efficiently? We’re going to test this hypothesis by teaching a Lean...

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This Will Save Us Years – Lean LaunchPad for Life Science

We’re deep into week 2 of teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) this October at UCSF with a team of veteran venture...

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300 Teams in Two Years

This is the start of the third year teaching teams of scientists (professors and their graduate students) in the National Science Foundation Innovation Corps (I-Corps). This month we’ve crossed ~300...

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Lean LaunchPad for Life Sciences – Value Proposition and Customers

We’re deep into teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) at UCSF with a team of veteran venture capitalists. (The class...

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Lean LaunchPad for Life Sciences – Distribution Channels

We’re teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) at UCSF with a team of veteran venture capitalists. The class has talked...

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Lean LaunchPad for Life Sciences – Revenue Streams

We’re teaching a Lean LaunchPad class for Life Sciences and Health Care (therapeutics, diagnostics, devices and digital health) at UCSF with a team of veteran venture capitalists. The class has talked...

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When Customers Make You Smarter

We talk a lot about Customer Development, but there’s nothing like seeing it in action to understand its power. Here’s what happened when an extraordinary Digital Health team gained several critical...

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We’ve seen the Future of Translational Medicine and it’s Disruptive

A team of 110 researchers and clinicians, in therapeutics, diagnostics, devices and digital health in 25 teams at UCSF, has just shown us the future of translational medicine.  It’s Lean, it’s fast, it...

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Lessons Learned in Digital Health

This post is part of our series on the National Science Foundation I-Corps Lean LaunchPad class in Life Science and Health Care at UCSF. Part 1:  issues in the therapeutics drug discovery pipeline Part...

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Lessons Learned in Medical Devices

This post is part of our series on the National Science Foundation I-Corps Lean LaunchPad class in Life Science and Health Care at UCSF. Doctors, researchers and Principal Investigators in this class...

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Lessons Learned in Therapeutics

This post is part of our series on the National Science Foundation I-Corps Lean LaunchPad class in Life Science and Health Care at UCSF. Doctors, researchers and Principal Investigators in this class...

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Lessons Learned in Diagnostics

This post is part of our series on the National Science Foundation I-Corps Lean LaunchPad class in Life Science and Health Care at UCSF. Doctors, researchers and Principal Investigators in this class...

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Why Lean May Save Your Life – The I-Corps @ NIH

Today the National Institutes of Health announced they are offering my Lean LaunchPad class (I-Corps @ NIH ) to commercialize Life Science. There may come a day that one of these teams makes a drug,...

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